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Home > 전제품보기 > 항체 · ELISA · Signal > IBL EIA Kit > Metabolism & Endocrine - FGF

Metabolism & Endocrine - FGF

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제조사 제품코드 제품명 용량 가격
(부가세별도)
비고 사용자매뉴얼
IBL
27996-96Well
Human FGF19 Assay Kit - IBL
관련학술 관심상품등록 구매하기
96 well
가격문의   제조사 페이지로 바로가기 27996_e.pdf
IBL
27997-96Well
Human FGF21 Assay Kit - IBL
관련학술 관심상품등록 구매하기
96 well
가격문의   제조사 페이지로 바로가기 27997_e.pdf

FGF19, FGF21
FGF19 subfamily composed of FGF19, FGF21 and FGF23 binds the receptors, α/β-Klotho and it is characterized as a factor group which has hormonal functions. The novel system consisted of α/β-Klotho and FGF19 subfamily regulates integrally metabolism of minerals, lipids, energy and amino acids. This novel regulating system involves important homeostatic mechanism for biological body such asmetabolism of bile acid and cholesterol in the liver (FGF19), energy and glycolipids metabolism (FGF21) and phosphate, calcium and vitamin D metabolism in kidney (FGF23) in fasting state.
FGF21 is secreted in the liver and it is reported that it has a lipolytic action in fatty tissues. FGF21 binds a receptor consisted of FGFR and βKlotho. FGF21 reacts in emptiness and it accelerates lipid metabolism in liver, Triacylglycerol (TG) is used as lipid acid and Ketone bodies are produced by the metabolism. As a result, it is used as an energy source. In this process, FGF21 is released and acts as a hormone-like factor. In relation to the concentration of FGF21 in blood, it is measured and reported that the correlation with many diseases like gestational diabetes mellitus, mitochondrial dysfunction in HIV infection, friedreich ataxia, coronary artery disease, carotid atherosclerosis, non-alcoholic fatty liver disease, rheumatoid arthritis, diabetic nephropathy, type2 diabetes, dyslipidemia and, obesity and metabolic syndrome.
관련 질병
당뇨병
보관
2 - 8 ℃
성능 및 적용 샘플

Code

제품명

검출 범위

적용 가능 샘플

27996-96Well

Human FGF19 Assay Kit - IBL

23.4 - 1,500 pg/mL

EDTA-plasma, cell culture supernatant

27997-96Well

Human FGF21 Assay Kit - IBL

31.3 - 2,000 pg/mL

Serum, EDTA-plasma, cell culture supernatant


Keyword : Incretin,insulin,glucagon,diabetes,당뇨,인슐린,당뇨병
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IBL EIA Kit
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> Inflammation & Cancer - COX-2
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> Metabolism & Endocrine - FGF
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> Metabolism & Endocrine - Leptin
> Metabolism & Endocrine - α-Klotho
> Metabolism & Endocrine – DPP4/CD26
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