18 | Tricking Toxins: a Fishing Tale
Researchers ask how the marine puffer fish leverages the deadly alkaloid tetrodotoxin without succumbing to it-and find some surprising answers. |
17 | Heading into Bat Caves on a Rescue Mission
In an effort to fight a devastating bat disease, scientists develop PCR assays to detect the pathogen in soil samples from bat caves. |
16 | Researchers Seek Early Signs of Neural Tube Defects
On a quest to identify biomarkers for neural tube defects, researchers use PrimeScript™ Reverse Transcriptase and SYBR® qPCR kits to identify miRNAs differentially expressed in maternal serum associated with the condition. |
15 | Building Better Biological Systems
By taking an engineering view of biology, synthetic biology researchers are creating entirely new genetic circuitry in E. coli-and In-Fusion® cloning systems make it fast and easy. |
14 | New Blood: Alleles Rarer than a Needle in a Haystack
While searching for a way to study genetic disease alleles that are tricky to detect due to somatic mosaicism, researchers found that an NGS-based approach using PrimeSTAR GXL polymerase gave the required level of sensitivity.
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13 | How the Leopard Lost Its Spots
An international team of scientists finds that the answer to how leopards produce panthers lies in single nucleotide polymorphisms. |
12 | Simplicity Conquers Complexity in Influenza Research
Influenza keeps making us sick because of complex diversity in viral types, subtypes, and strains, but an elegantly simple approach to cloning and sequencing viral samples may speed up research.
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11 | Boning Up on miRNA-regulated Osteoclast Development
Scientists identify a miRNA involved in osteoclast development, giving insight into the push-me-pull-you process of bone maintenance performed by osteoblasts and osteoclasts. |
10 | Hitting Back at Hepatitis B
In a quest for new strategies to combat Hepatitis B-caused hepatocellular carcinoma, scientists identified human miRNAs critical for disease progression.
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9 | Fighting Mosquitoes and Dengue Fever with a RIDL
This riddle's on the bugs: Researchers used the Tet-Off® system to develop the Release of Insects carrying a Dominant Lethal system for controlling mosquito populations. |
08 | Stem Cells Let Biologists Become Time Travelers
By "melting time" and turning back the developmental clock, Nobel Prize winners John Gurdon and Shinya Yamanaka revolutionized our understanding of mammalian cell differentiation.
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07 | Getting the Skinny on Fat with an Inducible Mouse Model
To understand the physiological role of adipocytes, researchers create a clever transgenic mouse model that allows them to obliterate fat cells at will. |
To reduce fuel consumption and landfill waste, an environmental stewardship program at the University of Washington encourages the use of energy-saving, waste-reducing reagents, such as EcoDry™products.
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Researchers engineer a patient's own lymphocytes to recognize cancer antigens, then return the engineered cells to the patient where they specifically target cancer cells. |
A deeper understanding of the signaling pathway for banana fruit ripening may be a first step to getting bananas from tree to table at the peak of perfection.
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Conventional RNA-Seq methods require over 10 ng of RNA from 100 cells, but researchers used the SMARTer® Ultra™ Low for Illumina® kit to study gene expression in a single circulating tumor cell with just 10 pg of input RNA. |
Hair traps and a sensitive PCR assay help conservation biologists monitor the population size of Asian Black Bears – from a safe distance.
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The humble jellyfish Aequorea victoria launched a life science research revolution by illuminating countless scientific explorations. |
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