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Home > 전제품보기 > microRNA 관련 > Inhibition for miRNA_Exiqon > miRCURY LNA microRNA Inihitor Libraries

miRCURY LNA microRNA Inihitor Libraries

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제조사 제품코드 제품명 용량 가격
(부가세별도)
비고 사용자매뉴얼
Exiqon
190104-1
miRCURY LNA microRNA inhibitor Library (0.25 nmol)- Human
관련학술 관심상품등록 구매하기
1set
가격문의  
Exiqon
190104-2
miRCURY LNA microRNA inhibitor Library (0.125 nmol)- Human
관련학술 관심상품등록 구매하기
1set
가격문의  
Exiqon
190105-1
miRCURY LNA microRNA Family Power Inhibitor Library (0.25 nmol) - human & mouse
관련학술 관심상품등록 구매하기
1set
가격문의  
Exiqon
190105-2
miRCURY LNA microRNA Family Power Inhibitor Library (0.125 nmol) - human & mouse
관련학술 관심상품등록 구매하기
1set
가격문의  
Exiqon
190204-1
miRCURY LNA microRNA inhibitor Library (0.25 nmol) - Mouse
관련학술 관심상품등록 구매하기
1set
가격문의  
Exiqon
190204-2
miRCURY LNA microRNA inhibitor Library (0.125 nmol) - Mouse
관련학술 관심상품등록 구매하기
1set
가격문의  

제품 설명
miRCURY LNA microRNA Inhibitor Libraries는 human과 mouse microRNA의 기능을 편리하고 빠르게, 대량으로 연구할 수 있는 high-throughput screening 제품이다. 본 제품은 Phosphodiester backbone을 보유한 Tm-normalized miRCURY LNA microRNA Inhibitor로 구성되었다.

miRCURY LNA™ microRNA Inhibitor는 최적의 길이와 서열, LNA 위치를 인식하는 디자인 알고리즘을 이용하여 개발되었다. 이는 self-complementarity는 최소화하는 반면, 뛰어난 특이성과 생물학적인 안정성을 결합하여 inhibitor로서의 높은 잠재력을 나타낸다.
특징
  • New improved design - ensures optimal performance of all inhibitors under the same conditions
  • Uniform high potency - inhibit all microRNAs equally well, regardless of GC content
  • Low toxicity and minimal secondary effects - efficient targeting of all microRNAs at low concentrations
  • High miRBase v. 20 coverage: 1,972 human inhibitors or 1,624 mouse inhibitors
  • Cost effective screening - inhibitors of microRNAs with no direct or very little experimental evidence are not included
  • Smarter screening workflows - start by screening the best characterized microRNAs due to intelligent plate design.
  • Practical 96-well plate format for high throughput screening
  • Comprehensive plate layout file with accurate up-to-date miRBase annotations

그림 1. miRCURY LNA™ microRNA Inhibitors are more efficient than competing technologies at inhibiting microRNAs. The expression of the pMIR-21 luciferase reporter is upregulated compared to the no-oligonucleotide control when MCF7 cells are transfected with antisense inhibitors directed against hsa-mir-21. This effect is significantly stronger in cells transfected with LNA™ oligonucleotides than cells transfected with DNA (Product A and B) or 2’-O-Me oligonucleotides. Measurements were taken 60 h after transfection.
Coverage
  • Human library: 1,972 inhibitors of human microRNAs listed in miRBase v. 20 - corresponding to a coverage of 78%.
  • Mouse library: 1,624 inhibitors of mouse microRNAs listed in miRBase v. 20 - corresponding to a coverage of 86%.
Plate layout
자세한 Inhibitor Plate layout은 아래 링크를 확인 부탁드립니다.
Detailed Plate layout file 보기

그림 2. Example of a miRCURY LNA™ microRNA Inhibitor Library plate This is the layout of panel 10 of the human microRNA inhibitor library.
상세설명

Code

제품명

상세설명

190103-1

miRCURY LNA™ microRNA inhibitor Library (0.25 nmol) - Human

microRNA Inhibitor Library - Human (1972 x 0.25 nmol)

190103-2

miRCURY LNA™ microRNA inhibitor Library (0.125 nmol) - Human

microRNA Inhibitor Library - Human (1972 x 0.125 nmol)

190203-1

miRCURY LNA™ microRNA inhibitor Library (0.25 nmol) - Mouse

microRNA Inhibitor Library - Mouse (1624 x 0.25 nmol)

190203-2

miRCURY LNA™ microRNA inhibitor Library (0.125 nmol) - Mouse

microRNA Inhibitor Library - Mouse (1624 x 0.125 nmol)


Keyword :
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Inhibition for miRNA_Exiqon
> miRCURY LNA microRNA Inhibitors and Power Inhibitors 검색
> miRCURY LNA microRNA Inhibitors and Power Inhibitors
> miRCURY LNA microRNA inhibitor_Controls
> Custom miRCURY LNA microRNA Inhibitors and Power Inhibitors
MicroRNA Family의 기능 분석에
> miRCURY LNA microRNA Family Inhibitors
> miRCURY LNA microRNA Inihitor Libraries
Exiqon만의 특화된 세가닥 Mimics을 이용한 기능분..
> miRCURY LNA microRNA Mimics
> miRCURY LNA microRNA Mimics - Controls
> miRCURY LNA microRNA Target Site Blockers
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