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Home > 전제품보기 > microRNA 관련 > Inhibition for miRNA_Exiqon > miRCURY LNA microRNA Inihitor Libraries

miRCURY LNA microRNA Inihitor Libraries

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제조사 제품코드 제품명 용량 가격
(부가세별도)
비고 사용자매뉴얼
Exiqon
190104-1
miRCURY LNA microRNA inhibitor Library (0.25 nmol)- Human
관련학술 관심상품등록 구매하기
1set
가격문의  
Exiqon
190104-2
miRCURY LNA microRNA inhibitor Library (0.125 nmol)- Human
관련학술 관심상품등록 구매하기
1set
가격문의  
Exiqon
190105-1
miRCURY LNA microRNA Family Power Inhibitor Library (0.25 nmol) - human & mouse
관련학술 관심상품등록 구매하기
1set
가격문의  
Exiqon
190105-2
miRCURY LNA microRNA Family Power Inhibitor Library (0.125 nmol) - human & mouse
관련학술 관심상품등록 구매하기
1set
가격문의  
Exiqon
190204-1
miRCURY LNA microRNA inhibitor Library (0.25 nmol) - Mouse
관련학술 관심상품등록 구매하기
1set
가격문의  
Exiqon
190204-2
miRCURY LNA microRNA inhibitor Library (0.125 nmol) - Mouse
관련학술 관심상품등록 구매하기
1set
가격문의  

제품 설명
miRCURY LNA microRNA Inhibitor Libraries는 human과 mouse microRNA의 기능을 편리하고 빠르게, 대량으로 연구할 수 있는 high-throughput screening 제품이다. 본 제품은 Phosphodiester backbone을 보유한 Tm-normalized miRCURY LNA microRNA Inhibitor로 구성되었다.

miRCURY LNA™ microRNA Inhibitor는 최적의 길이와 서열, LNA 위치를 인식하는 디자인 알고리즘을 이용하여 개발되었다. 이는 self-complementarity는 최소화하는 반면, 뛰어난 특이성과 생물학적인 안정성을 결합하여 inhibitor로서의 높은 잠재력을 나타낸다.

miRCURY LNA microRNA Family Power Inhibitor는 각각의 microRNA(miRNA)가 아니라 microRNA family 전체를 저해하도록 디자인된 LNA microRNA inhibitor이다. miRCURY LNA microRNA Family Power Inhibitor는 96 well plate type으로 구성되어있다.
특징
  • New improved design - ensures optimal performance of all inhibitors under the same conditions
  • Uniform high potency - inhibit all microRNAs equally well, regardless of GC content
  • Low toxicity and minimal secondary effects - efficient targeting of all microRNAs at low concentrations
  • High miRBase v. 20 coverage: 1,972 human inhibitors or 1,624 mouse inhibitors
  • Cost effective screening - inhibitors of microRNAs with no direct or very little experimental evidence are not included
  • Smarter screening workflows - start by screening the best characterized microRNAs due to intelligent plate design.
  • Practical 96-well plate format for high throughput screening
  • Comprehensive plate layout file with accurate up-to-date miRBase annotations

그림 1. miRCURY LNA™ microRNA Inhibitors are more efficient than competing technologies at inhibiting microRNAs. The expression of the pMIR-21 luciferase reporter is upregulated compared to the no-oligonucleotide control when MCF7 cells are transfected with antisense inhibitors directed against hsa-mir-21. This effect is significantly stronger in cells transfected with LNA™ oligonucleotides than cells transfected with DNA (Product A and B) or 2’-O-Me oligonucleotides. Measurements were taken 60 h after transfection.
Coverage
  • Human library: 1,972 inhibitors of human microRNAs listed in miRBase v. 20 - corresponding to a coverage of 78%.
  • Mouse library: 1,624 inhibitors of mouse microRNAs listed in miRBase v. 20 - corresponding to a coverage of 86%.
Plate layout
자세한 Inhibitor Plate layout은 아래 링크를 확인 부탁드립니다.
Detailed Plate layout file 보기

그림 2. Example of a miRCURY LNA™ microRNA Inhibitor Library plate This is the layout of panel 10 of the human microRNA inhibitor library.
상세설명

Prod.No.

Product Name

Description

190104-1

miRCURY LNA microRNA inhibitor Library (0.25 nmol)- Mouse

microRNA Inhibitor Library - Human (1972 x 0.25 nmol)

190104-2

miRCURY LNA microRNA inhibitor Library (0.125 nmol)- Mouse

microRNA Inhibitor Library - Human (1972 x 0.125 nmol)

190105-1

miRCURY LNA microRNA Family Power Inhibitor Library (0.25 nmol) - human & mouse

microRNA Family Power inhibitor library - Human & Mouse (43 x 0.25 nmol)

190105-2

miRCURY LNA microRNA Family Power Inhibitor Library (0.125 nmol) - human & mouse

microRNA Family Power inhibitor library - Human & Mouse (43 x 0.125 nmol)

190204-1

miRCURY LNA microRNA inhibitor Library (0.25 nmol) - Mouse

microRNA Inhibitor Library - Mouse (1624 x 0.25 nmol)

190204-2

miRCURY LNA microRNA inhibitor Library (0.125 nmol) - Mouse

microRNA Inhibitor Library - Mouse (1624 x 0.125 nmol)


Keyword :
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Inhibition for miRNA_Exiqon
> miRCURY LNA microRNA Inhibitors and Power Inhibitors 검색
> miRCURY LNA microRNA Inhibitors and Power Inhibitors
> miRCURY LNA microRNA inhibitor_Controls
> Custom miRCURY LNA microRNA Inhibitors and Power Inhibitors
MicroRNA Family의 기능 분석에
> miRCURY LNA microRNA Family Inhibitors
> miRCURY LNA microRNA Inihitor Libraries
Exiqon만의 특화된 세가닥 Mimics을 이용한 기능분..
> miRCURY LNA microRNA Mimics
> miRCURY LNA microRNA Mimics - Controls
> miRCURY LNA microRNA Target Site Blockers
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