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 Á¦¸ñ : [À̺¥Æ® Á¾·á] [ÇÁ·Î¸ð¼Ç] ÀÓ»ó¸ñÀû ÃÖÀû Lentivirus ½Ã½ºÅÛ LVpro 20% ÇÒÀÎ Áß!!
ÀÛ¼ºÀÏ : 2024.03.22
 ÀÛ¼ºÀÚ : ´ÙÄ«¶óÄÚ¸®¾Æ

ÀÓ»ó ¸ñÀû¿¡ ÃÖÀûÈ­µÈ Lentivirus »ý»ê ½Ã½ºÅÛ LVpro¢â


ÀÓ»ó ¸ñÀûÀ¸·Î lentivirus¸¦ Á¦ÀÛÇÏ¿© CAR-T¿Í °°Àº CGT ºÐ¾ß¿¡¼­ »ç¿ëÇÏ´Â °æ¿ì transgeneÀÌ Àå±â°£ Ÿ°Ù ¼¼Æ÷¿¡¼­ ¹ßÇöµÇ±â ¶§¹®¿¡ º¸´Ù ¾ÈÁ¤Àû°í ±â´ÉÀûÀÎ vector¸¦ ¼±ÅÃÇØ¾ß ÇÕ´Ï´Ù.

´ç»ç¿¡¼­´Â ¾ÈÀü¼ºÀ» À§ÇØ HIVÀ¯·¡ ¼­¿­À» ÇÑ°è±îÁö °¨¼Ò½ÃŲ 3¼¼´ë Lentivirus »ý»ê ½Ã½ºÅÛ (LVpro¢â)À» ÆǸÅÇÏ°í ÀÖ½À´Ï´Ù.

 

LVpro¢â ½Ã¸®Áî Ư¡

  • pLVpro VectorÀÇ Æ¯Â¡
    - 5¡¯-LTRÀÇ U3 ¿µ¿ªÀ» CMV ÇÁ·Î¸ðÅͷΠġȯ (¨ç tat-independent)
    - Vector¿¡ HIV-1À¯·¡ÀÇ Gag ¼­¿­À» ÇÑ°è±îÁö Á¦°Å (¨è RCL ¹ß»ý À§Çè °¨¼Ò)
    - WPRE ¼­¿­ÀÇ X protein ¹ßÇöÀ» ¾ïÁ¦ (¨é Å¸°Ù ¼¼Æ÷ÀÇ tumorigenesis À¯¹ß È®·ü °¨¼Ò)
    - 3Á¾ÀÇ promoter¸¦ ½ÇÇ躰·Î ÃÖÀûÀ¸·Î ¼±Åà °¡´É (MSCV, MSCV-E1, EF1¥á) 
  • LVpro¢â Packaging MixÀÇ Æ¯Â¡
    - Lentivirus »ý»êÀ» À§ÇÑ ¿©·¯ packaging plasmid (env (VSV-G), gag, pol, rev ¹ßÇö)¸¦ premix ÇüÅ·ΠÁ¦°øÇÏ¿© °£´ÜÇÑ ½ÇÇè °¡´É.
    - ½ÇÇèÁ¶°Ç ÃÖÀûÈ­ ¹× ½ÇÇè¼ÂÆà °úÁ¤À» °ÅÄ¡Áö ¾Ê°íµµ °í¿ª°¡ lentivirus »ý»êÀÌ °¡´É.

   

ÁÖ¿äÁ¦Ç°

Code

Á¦Ç°¸í

¿ëµµ

6195

LVpro¢â Packaging Mix

Packaging plasmids premix

6962

LVpro¢â Packaging Mix (pLVpro-MSCV Vector)

pLVpro Vector Æ÷ÇÔ*

6963

LVpro¢â Packaging Mix (pLVpro-MSCV-EI Vector)

6964

LVpro¢â Packaging Mix (pLVpro-EF1¥á Vector)

6965

LVpro¢â Packaging Mix (pLVpro-MSCV-ZsGreen1 Vector)

ZsGreen1ÀÇ control plasmid Æ÷ÇÔ*

* #6962~#6967 Á¦Ç°Àº LVpro¢â Packaging Mix (Code 6195)¿¡ °¢ pLVpro Vector (0.5 §¶/§¡, 40 §¡)·Î ±¸¼ºµÇ¾î ÀÖÀ½.




±×¸² 1. pLVpro Vector ±¸Á¶ 


´Ù¼öÀÇ ÀÓ»ó»ç·Ê¸¦ º¸À¯ÇÑ lentivirus transduction enhancerµµ ÀÖ½À´Ï´Ù.


 

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Á¦Ç° °ü·ÃµÈ ¹®ÀÇ»çÇ×Àº °í°´Áö¿ø (02-2081-2510, support@takara.co.kr·Î ¿¬¶ô ¹Ù¶ø´Ï´Ù.  

 

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