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Home > ´ÙÄ«¶ó ½ºÆ©µð¿À > ¼îÄÉÀ̽º > ÀÓ»ó¿ë lentivirus, ¾ÈÀü°ú È¿À²À» ÃÖ´ë·Î


ÀÓ»ó¿ë lentivirus, ¾ÈÀü°ú È¿À²À» ÃÖ´ë·Î
Receptor ±â¹Ý transduction enhancer (GMPµµ º¸À¯)
RetroNectin¢ç (Code T100A ¿Ü)
- Lentivirus / RetrovirusÀÇ transduction enhancer·Î RetroNectinÀÇ Heparin-binding domainÀÌ ¹ÙÀÌ·¯½º¿Í °áÇÕÇÑ µÚ Cell-binding domain°ú ¼¼Æ÷°¡ °áÇÕÇØ transductionÀ» ÃËÁøÇÑ´Ù. ÈçÈ÷ »ç¿ëÇÏ´Â chemical ±â¹ÝÀÇ polybrene, protamine°ú ºñ±³ÇØ µ¶¼ºÀÌ ¸Å¿ì ³·°í È¿À²ÀÌ ³ô¾Æ ±âÁ¸¿¡´Â ¹ÙÀÌ·¯½º µµÀÔÀÌ ¾î·Á¿ü´ø suspension cell, primary cell, stem cellÀÇ transduction È¿À²À» ³ôÀ̴µ¥ ³Î¸® »ç¿ëµÇ°í ÀÖ½À´Ï´Ù.
- T-cell È®´ë¹è¾ç¿¡µµ Àû¿ëÇÒ ¼ö ÀÖ¾î CAR-T ¿¬±¸¿¡µµ ÃÖÀûÀÇ Á¦Ç°ÀÔ´Ï´Ù. (T-cell È®´ë¹è¾ç ¼Ö·ç¼Ç).

HIV ¼­¿­À» ±Øµµ·Î ÁÙ¿© ÀÓ»ó½ÇÇè¿¡ ÃÖÀûÈ­½ÃŲ 3¼¼´ë lentivirus ½Ã½ºÅÛ
LVpro¢â Packaging Mix (pLVpro Vector) (Code 6962 ¿Ü)
- HIV-1 À¯·¡ÀÇ tat ¼­¿­ÀÌ Á¦°ÅµÇ°í, 3¡¯ LTRÀÇ ÀϺμ­¿­ °á¼ÕÀ¸·Î ¹ÙÀÌ·¯½ºÀÇ ÀÚ°¡ º¹Á¦¸¦ ¹æÁöÇÏ´Â µî (self-inactivation; SIN) 3¼¼´ë lentivirusÀÇ Æ¯Â¡À» °¡Áö°í ÀÖ½À´Ï´Ù. ƯÈ÷ HIV-1 À¯·¡ ¼­¿­À» ÇÑ°èÄ¡±îÁö Á¦°ÅÇØ ¾ÈÀü¼ºÀ» ³ô¿© ÀÓ»ó ¿¬±¸¿¡ ÃÖÀûÀÎ Á¡ÀÌ Æ¯Â¡ÀÔ´Ï´Ù. Lentivirus »ý»ê¿¡ ÇÊ¿äÇÑ ¸ðµç packaging plasmid (env, gag, pol, rev ¹ßÇö)¸¦ premix ÇüÅ·ΠÁ¦°øÇÏ¿© °£´ÜÇÏ°Ô ½ÇÇèÀ» ÁøÇàÇÒ ¼ö ÀÖ½À´Ï´Ù.

Cell & Gene therapy ¿¬±¸¸¦ ÇÑ´Ù¸é,
RetroNectin¢ç°ú LVpro¢â, ÀÌ ÃÖ°íÀÇ Á¶ÇÕÀ» ¼±ÅÃÇØ ÁÖ¼¼¿ä.


*Âü°íÀÚ·á
- Lentivirus ¼±Åð¡À̵å

*°ü·Ã Á¦Ç°
- ½ÇÇè ÈÄ ÀÜ·ùÇÑ RetroNectin¢çÀ» ELISA·Î È®ÀÎ RetroNectin¢ç EIA Kit (Code MK140)
- RetroNectin¢çÀÇ GMP grade ¹öÀü RetroNectin¢ç GMP grade (Code T202)
- 1step qRT-PCR·Î ºü¸£°í Á¤È®ÇÑ ¿ª°¡ ÃøÁ¤ Lenti-X¢â qRT-PCR Titration Kit (Code 631235)
- 1.5½Ã°£À¸·Î ºü¸£°Ô ³¡³ª´Â ELISA¹ý ¿ª°¡ ÃøÁ¤ Lenti-X¢â p24 Rapid Titer Kit (Single Wash) (Code 631476)
- Lentivirus ³óÃàÀ» ÀϹݿø½ÉºÐ¸®±â·Î 1½Ã°£¸¸¿¡ Lenti-X¢â Concentrator (Code 631231)