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Anti-CD3 mAb GMP grade

-

Á¦Á¶»ç Á¦Ç°ÄÚµå Á¦Ç°¸í ¿ë·® °¡°Ý
(ºÎ°¡¼¼º°µµ)
ºñ°í »ç¿ëÀڸŴº¾ó
Takara
T210
Anti-CD3 mAb GMP grade
°ü·ÃÇмú ±¸¸ÅÇϱ⠶óÀ̼±½º 
1.0 mg/1.0 ml
2,515,000¿ø  T210_DS.v2402.pdf





¡ØAnti-CD3 mAb GMP grade (Code T210) Á¦Ç° ÁÖ¹®½Ã Àü¿ë ÁÖ¹®¼­¸¦ ÀÛ¼ºÇÏ¿© ´ÙÄ«¶óÄÚ¸®¾Æ(support@takara.co.kr)·Î º¸³»ÁÖ¼¼¿ä.
Á¦Ç°¼³¸í
º» Á¦Ç°Àº GMP gradeÀÇ Anti-CD3 monoclonal antibody·Î¼­ T cellÀÇ Áõ½Ä ÀÚ±ØÇÏ¿©, È®´ë¹è¾ç½Ã (expansion) »ç¿ëµÈ´Ù. Anti-CD3 mAb GMP grade´Â °¡Àå ÀϹÝÀûÀ¸·Î T cell È®´ë¹è¾ç¿¡ »ç¿ëµÇ´Â ¡®OKT3¡¯ Clone (mouse IgG2a)À¸·Î Á¦À۵ǾúÀ¸¸ç, º» Á¦Ç°°ú RetroNectin¢ç (Code T100A)À» ÇÔ²² »ç¿ëÇϸé, T cellÀ» °¡Àå È¿À²ÀûÀ¸·Î È®´ë¹è¾ç ÇÒ ¼ö ÀÖ´Ù.
GMP grade·Î Á¦Á¶ ¹× Ç°Áú °ü¸®µÈ Á¦Ç°À¸·Î, ex-vivo¿¡¼­ÀÇ À¯ÀüÀÚ Ä¡·á¿Í ¼¼Æ÷ Á¦ÀÛ µîÀÇ Àӻ󿬱¸¿¡ »ç¿ë °¡´ÉÇÏ´Ù.

(A) È®´ë¹è¾ç·ü


(B) CD3/CD4/CD8 ºñÀ²


(C) ¼¼Æ÷ µ¶¼º È°¼º ÃøÁ¤

±×¸² 1. T cellÀÇ È®´ë¹è¾ç¿¡¼­ OKT3ÀÇ ¼º´É ºñ±³. Peripheral blood mononuclear cell (PBMC)À» Anti-CD3 mAbÀÇ ÀÚ±ØÇÏ¿¡¼­ 5ÀÏ°£ ¹è¾ç ÈÄ, T cell ¹è¾ç ¹èÁö¿¡ ÀûÀýÈ÷ Èñ¼®Çϸ鼭
9ÀÏ°£ Ãß°¡ ¹è¾çÇÏ¿´´Ù. È®´ë¹è¾ç ÈÄ (A) ¼¼Æ÷ Áõ½Ä·ü, (B) Ç¥ÇöÇü (CD3/CD4/CD8 ºñÀ²), (C) K562¼¼Æ÷ÀÇ ¼¼Æ÷ µ¶¼º È°¼ºÀ» ºñ±³ÇÑ °á°ú, Anti-CD3 GMP grade´Â Ÿ»ç Á¦Ç°°ú µ¿µîÇÑ ¼º´ÉÀ» ³ªÅ¸³»¾ú´Ù.
º¸Á¸
-70¡É ÀÌÇÏ¿¡¼­ º¸°ü
±â¿ø
Mouse Hybridoma cells
¼øµµ
>95% by HPLC
Æ÷Àå ÇüÅÂ
1.0 §· protein / 1.0 §¢ÀÇ ¿ë¾× Á¦Ç°À» 2 §¢ cryovial¿¡ Æ÷Àå
Application
  • CIK (cytokine-induced killer)ÀÇ È®´ë¹è¾ç (Cytokine°ú ÇÔ²² »ç¿ë)
  • T lymphocyteÀÇ È®´ë¹è¾ç (RetroNectin¢ç°ú ÇÔ²² »ç¿ë)
T cell È®´ë¹è¾ç °ü·ÃÁ¦Ç°

Code

Á¦Ç°¸í

¿ë·®

T100A

RetroNectin¢ç Recombinant Human Fibronectin Fragment

0.5 §·

T100B

RetroNectin¢ç Recombinant Human Fibronectin Fragment

2.5 §·

T202

RetroNectin¢ç GMP Grade

2.5 §·/§¢

FU0005

CultiLife¢â 215 Culture bag

10 ¸Å

FU0010

GT-T610 (CultiLife¢â Eva) Culture bag

10 ¸Å

WK551S

GT-T551 Culture medium, 1L Bottle

1,000 §¢


Keyword : OKT3,okt3,car-t,CAR-T,Tcell,t cell,t-cell